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CTMS Module 14 of 29

Central Monitoring

Real-time centralized monitoring with automated alerts and cross-site trend detection.

Module Overview

The Central Monitoring module provides real-time centralized monitoring of trial data with automated alert generation, cross-site trend detection, and statistical anomaly identification. It complements on-site monitoring by continuously analyzing data streams from EDC, safety, and operational systems to detect issues that may not be visible during periodic site visits.

Key Features

Real-time data stream monitoring
Automated alert generation for KRI breaches
Statistical anomaly detection (outliers, trends)
Cross-site comparison and benchmarking
Risk-based alert prioritization
Central monitoring report generation

Workflow & Interface

Explore the module's workflow through interactive interface mockups showing each step of the process.

1

Real-Time Alert Dashboard

Centralized dashboard showing all active alerts with severity, site, and KRI details.

medifirm-ctms — module view

Alert #042

Site D — Query rate spike

High

Alert #041

Site B — AE reporting delay

Medium

Alert #040

Site E — Enrollment velocity drop

Medium

Alert #039

Site A — Protocol deviation trend

Low

Alert #038

Site C — Data entry lag

Resolved
2

Cross-Site Trend Analysis

Statistical comparison of site performance metrics to identify outliers and emerging trends.

medifirm-ctms — module view
Site A — Query Rate
32%
Site B — Query Rate
45%
Site C — Query Rate
28%
Site D — Query Rate
82%
Site E — Query Rate
38%
Site F — Query Rate
35%
3

Central Monitoring Report

Automated summary of monitoring activities, alerts triggered, and actions taken.

medifirm-ctms — module view

Active Alerts

7

2 high priority

Alerts This Month

34

-22% vs last month

Mean Resolution

3.2 days

Within 5-day SLA

Sites Monitored

42/42

100% coverage

Module Connections

How Central Monitoring integrates with other CTMS modules in the platform.

Receives fromRBQM Plan

KRIs define alert thresholds

View Module
BidirectionalRBM Plan

Alerts trigger adaptive monitoring changes

View Module
Receives fromEDC & Data Capture

Real-time data feeds for monitoring

View Module
Receives fromSafety & Pharmacovigilance

Safety signals generate alerts

View Module
Sends toRisk & Issue Management

Alerts create issues in risk register

View Module
BidirectionalAI Agent Recommendations

AI analyzes alert patterns for insights

View Module